| Dartmouth Electron Microscope Facility | Date: Tue 07-Jun-2011 Time: 16:31 |
 01_HIV-tc1.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard.
Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
To see a short video
about HIV infection pathway go to: |
 02_hiv-tc2.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard.
Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of
acquired immune deficiency syndrome (AIDS). HIV is a
retrovirus. The major host cell of HIV is the CD4 class
of T lymphocytes and the virus somehow prevents normal
division processes in these cells. Lymphocytes are very
important to the body's immune functions. This viral
infection process greatly compromises those immune
functions, by the accelerated reduction of CD4 cells;
this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
To see a short video
about HIV infection pathway go to: |
 03_hiv-tc3.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 04_hiv-tc4.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more info see: |
 05_hiv-tc5.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1) virus attaches to the cell via the CD4 molecule on the surface of the cell. The CD4 molecule on the lymphocyte acts as a cell surface receptor for HIV. (2) fusion of the virus envelope with the host cell membrane. (3) nucleocapsid, containing the genetic material, is carried into cytoplasm by endocytosis.
To see a short video
about HIV infection pathway go to: |
 06_hiv-tc11-07-3.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 07_hiv-tc11-07-1.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
For more information see: HIV infection pathway_short video |
 08_HIV-tc-2008-1.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1) virus attaches to the cell via the CD4 molecule on the surface of the cell. The CD4 molecule on the lymphocyte acts as a cell surface receptor for HIV. (2) fusion of the virus envelope with the host cell membrane. (3) nucleocapsid, containing the genetic material, is carried into cytoplasm by endocytosis.
HIV infection pathway_short video |
 09_Grid3c_HIV4-3.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 10_Grid3c_HIV4-2.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 11_Grid3c_HIV4-1.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 12_HIV_Apr26_2011-1.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 13_HIV_Apr26_2011-2.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
HIV infection pathway_short video |
 14_HIV_Apr26_2011-3.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 15_HIV_Apr26_2011-4.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS. The process of infection: (1) virus attaches to the cell via the CD4 molecule on the surface of the cell. The CD4 molecule on the lymphocyte acts as a cell surface receptor for HIV. (2) fusion of the virus envelope with the host cell membrane. (3) nucleocapsid, containing the genetic material, is carried into cytoplasm by endocytosis.
HIV infection pathway_short video |
 16_HIV
TC 40736 6,6kx.jpg |
Instrument: JEOL 100CX TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of
acquired immune deficiency syndrome (AIDS). HIV is a
retrovirus. The major host cell of HIV is the CD4 class
of T lymphocytes and the virus somehow prevents normal
division processes in these cells. Lymphocytes are very
important to the body's immune functions. This viral
infection process greatly compromises those immune
functions, by the accelerated reduction of CD4 cells;
this, in turn leads to AIDS. The process of infection: (1) virus attaches to the cell via the CD4 molecule on the surface of the cell. The CD4 molecule on the lymphocyte acts as a cell surface receptor for HIV. (2) fusion of the virus envelope with the host cell membrane. (3) nucleocapsid, containing the genetic material, is carried into cytoplasm by endocytosis. |
 17_HIV
TC 2104 10kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of
acquired immune deficiency syndrome (AIDS). HIV is a
retrovirus. The major host cell of HIV is the CD4 class
of T lymphocytes and the virus somehow prevents normal
division processes in these cells. Lymphocytes are very
important to the body's immune functions. This viral
infection process greatly compromises those immune
functions, by the accelerated reduction of CD4 cells;
this, in turn leads to AIDS. The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: To see a short video about
HIV infection pathway go to: |
 18_HIV
TC 2101 100kx.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
For more information see:
HIV infection pathway_short video |
 19_HIV
TC 2102 25kx.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: To see a short video about HIV infection pathway go to: HIV infection pathway_short video |
 20_HIV
TC 2106 50kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 21_HIV
TC 2108 25kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see: HIV infection pathway_short video |
 22_HIV
TC 2109 25kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
For more information see: To see a short video about HIV infection pathway go to: HIV infection pathway_short video |
 23_HIV
TC 2112 25kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
For more information see: HIV infection pathway_short video |
 24_HIV
TC 2111 50kX.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis.
For more information see: HIV infection pathway_short video |
 25_HIV
TC 2114 6Kx.jpg |
Instrument: JEOL 1010 TEM Microscopist: Louisa Howard. Tissue culture cell line, infected with human immunodeficiency virus (HIV) HIV particles are 90-120nm in diameter.
HIV is the causal agent of acquired immune deficiency syndrome (AIDS). HIV is a retrovirus. The major host cell of HIV is the CD4 class of T lymphocytes and the virus somehow prevents normal division processes in these cells. Lymphocytes are very important to the body's immune functions. This viral infection process greatly compromises those immune functions, by the accelerated reduction of CD4 cells; this, in turn leads to AIDS.
The process of infection: (1)
virus attaches to the cell via the CD4 molecule on the
surface of the cell. The CD4 molecule on the lymphocyte
acts as a cell surface receptor for HIV. (2) fusion of
the virus envelope with the host cell membrane. (3)
nucleocapsid, containing the genetic material, is
carried into cytoplasm by endocytosis. For more information see:
|